EphA2 bears plasticity to tumor invasion
نویسندگان
چکیده
منابع مشابه
EphA2 bears plasticity to tumor invasion
During metastatic tumor progression, cancer cells are exposed to different microenvironments. The microenvironment with which they negotiate within primary tumor is unlike the one they encounter when invading into stroma or vasculature, and different also from what they will be exposed to as they spread into secondary sites. Therefore, one property that cancer cells acquire is plasticity. The c...
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Invasive and proliferative phenotypes are fundamental components of malignant disease, yet basic questions persist about whether tumor cells can express both phenotypes simultaneously and, if so, what are their properties. Suitable in vitro models that allow characterization of cells that are purely invasive are limited because proliferation is required for cell maintenance. Here, we describe g...
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Calcifying odontogenic cyst (COC) is a unique odontogenic lesion with combined features of a cyst and neoplasm. This lesion shows a great diversity in its clinicopathological behavior. It may become aggressive and rarely malignant. This case is an aggressive COC of the maxilla in a young male patient which recurred after several radical surgical excisions. Eventually invading the cranium, t...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2013
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.26180